Preheat your oven to 375°F (190°C).
Cook the penne or rotini according to package instructions until al dente; drain and set aside.
In a large skillet, heat olive oil over medium heat. Add cubed chicken and Cajun seasoning; cook until browned (about 5–7 minutes).
Remove the chicken and sauté diced onion, red bell pepper, and minced garlic in the same skillet for about 3–4 minutes.
Stir in cream cheese until melted; then add heavy cream and chicken broth to create a smooth sauce.
Mix in shredded cheddar and Parmesan cheese until creamy.
Combine cooked chicken with the sauce and drained pasta; mix well.
Transfer the mixture to a greased baking dish and bake for 20–25 minutes until bubbly and golden brown.
Let cool slightly before serving hot.
